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Published on 5/1/2006 in the Prospect News Biotech Daily.

Cardiokine closes $50 million series B financing

By Lisa Kerner

Erie, Pa., May 1 - Cardiokine, Inc. said it closed a $50 million series B preferred share equity offering.

The funds will be used to start phase 3 trials for its lead product candidate, Lixivaptan, a selective V2 vasopressin receptor antagonist for the treatment of hyponatremia, a sodium imbalance that contributes to poor outcomes in a number of disorders, including heart failure and cirrhosis.

New investors Advent Venture Partners and Fidelity Biosciences co-led the financing round, joined by Teachers Private Capital. All of Cardiokine's series A investors, including Perseus-Soros Biopharmaceutical Fund, HealthCare Ventures, Care Capital, CIBC Capital Partners and Burrill & Co. participated in the series B financing.

Shahzad Malik, general partner at Advent Venture Partners, and Stephen Knight, managing partner of Fidelity Biosciences, will join Cardiokine's board of directors.

Located in Philadelphia, Cardiokine is a privately held specialty pharmaceutical company focused on the treatment and prevention of heart failure and related cardiovascular and metabolic indications.

Issuer:Cardiokine, Inc.
Issue:Series B preferred share equity
Amount:$50 million
Investors:Advent Venture Partners and Fidelity Biosciences (co-lead), Teachers Private Capital, Perseus-Soros Biopharmaceutical Fund, HealthCare Ventures, Care Capital, CIBC Capital Partners, Burrill & Co.
Announcement date:May 1

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