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Published on 4/25/2006 in the Prospect News Biotech Daily.

Nanogen adds EBV-detecting real-time probes and primers to portfolio

By Lisa Kerner

Erie, Pa., April 25 - Nanogen, Inc.'s expanded molecular reagent product portfolio now includes real-time probes and primers designed to detect the presence of Epstein-Barr virus (EBV), which causes infectious mononucleosis and underlies other lymphoproliferative disorders such as Burkitt's lymphoma.

The company said its MGB Alert EBV analyte-specific reagent can be used to develop and validate assays to detect sequences within the putative membrane antigen p140 region of the viral BNRF1 gene.

Particularly at risk for EBV-associated lymphoproliferation are people undergoing stem cell or solid organ transplantation. Lymphoproliferation may lead to post-transplant lymphoproliferative disorder; an infectious-mono like illness that can mimic transplant rejection.

"The EBV reagent is the newest addition to our growing menu of MGB Alert products, which includes [analyte-specific reagents] designed to detect sequences associated with herpes simplex viruses 1 and 2, cytomegalovirus, enterovirus, Chlamydia pneumoniae, Mycoplasma pneumoniae, and norovirus 1 and 2, among others," chairman and chief executive officer Howard Birndorf said in a company news release.

Nanogen, based in San Diego, develops diagnostic products and technologies for use by researchers, clinicians and physicians.


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