Cyprotex Cloe PK system studies to be published in peer-review journal

By E. Janene Geiss

Philadelphia, Oct. 27 - Cyprotex plc said Thursday it has received peer-approved publication of its Cloe PK system, a "virtual human and rat" system that allows drug testing without the use of animals.

Details of extensive validation results for Cloe PK, showing how the technology can estimate blood levels of new drugs without animal testing, has been accepted for publication by peer review journal, "Drug Metabolism and Disposition," according to a company news release.

Officials said Cyprotex also has been awarded a grant by the U.K. Department of Trade & Industry to extend the group's predictive technologies used in the invention of new drugs.

"This technology, along with new methodologies which we will develop as a result of the ... grant, will help us to make the next step in our drive towards understanding and eradicating the problems associated with how new drugs are processed by the body," said David Leahy, Cyprotex's founder and chief technical officer, said in the release.

The company recently announced that it is forming its own research group, Cyprotex Research Ltd., which will be aimed at eradicating drug liabilities from the very earliest stages of drug discovery.

The research group will form academic and industrial collaborations to develop computational capabilities to help improve research and development productivity throughout the industry, company officials said.

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