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Published on 9/5/2006 in the Prospect News Biotech Daily.

Cordis' Cypher stent slightly more effective than Taxus stent, data shows

By Elaine Rigoli

Tampa, Fla., Sept. 5 - Cordis Corp. said Tuesday that patients who received the Cypher Sirolimus-eluting coronary stent were less prone to experience heart attacks (Q-wave myocardial infarctions) or blood clots (stent thromboses) than patients treated with Boston Scientific's Taxus stent, according to two-year data from a prospective, randomized, multi-center study.

The data showed that less than 1% of the patients in the Cypher stent arm experienced stent thrombosis. In contrast, 2.5% of the patients in the Taxus stent arm suffered a blood clot.

In addition, the Miami Lakes, Fla., medical-device company said patients treated with the Cypher stent suffered a Q-wave myocardial infarction (a heart attack affecting the full thickness of the heart wall) much less frequently than those receiving the Taxus stent (0.1% vs. 1.5%).

Other major adverse cardiac events were also tracked, but a composite of these did not show a statistical difference between the two drug-eluting stents.


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